Role of Hybrid Brain Imaging in Neuropsychiatric Disorders

Diagnostics

Amer M. Burhan³  Nicole M. Marlatt³  Lena Palaniyappan²  Udunna C. Anazodo¹  Frank S. Prato¹ 

[1] Lawson Health Research Institute, London, ON N6C 2R5, Canada; E-Mails:;Department of Psychiatry, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON N6C 2R6, Canada; E-Mail:;St. Joseph’s Health Care London, Parkwood Institute, 550 Wellington Road, London, ON N6C 0A7, Canada; E-Mail:

关键词: neuropsychiatric disorders;    neuroimaging;    humans;    brain disorders/diagnosis;    hybrid imaging;    molecular imaging;    neuronal networks;    Alzheimer’s disease;    schizophrenia;    affective disorders;   

DOI  :  10.3390/diagnostics5040577

来源: mdpi

【 摘 要 】

This is a focused review of imaging literature to scope the utility of hybrid brain imaging in neuropsychiatric disorders. The review focuses on brain imaging modalities that utilize hybrid (fusion) techniques to characterize abnormal brain molecular signals in combination with structural and functional changes that have been observed in neuropsychiatric disorders. An overview of clinical hybrid brain imaging technologies for human use is followed by a selective review of the literature that conceptualizes the use of these technologies in understanding basic mechanisms of major neuropsychiatric disorders and their therapeutics. Neuronal network abnormalities are highlighted throughout this review to scope the utility of hybrid imaging as a potential biomarker for each disorder.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.