Bioactive Constituents from the Aerial Parts of Lippia triphylla

Molecules

Yi Zhang¹  Yue Chen¹  Shiyu Wang²  Yongzhe Dong¹  Tingting Wang²  Lu Qu¹  Nan Li²  Tao Wang² 

[1] Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China;Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshan Road, Nankai District, Tianjin 300193, China;

关键词: Lippia triphylla;    lippianoside;    structure elucidation;    antioxidant;    triglyceride accumulation inhibition;    L6 cells;    HepG2 cells;   

DOI  :  10.3390/molecules201219814

来源: mdpi

【 摘 要 】

Five new compounds, lippianosides A (1), B (2), C (3), D (4), and E (5), along with 26 (6–31) known ones were obtained from the 95% EtOH extract of Lippia triphylla (L. triphylla) aerial parts collected from Rwanda, Africa. Among the known compounds, 11 and 17–30 were isolated from the Lippia genus for the first time. In addition, 12, 13, and 16 were firstly obtained from this species. The structures of them were elucidated by chemical and spectroscopic methods. The antioxidant and triglyceride accumulation inhibition effects of the 31 compounds were examined in L6 cells and HepG2 cells, respectively.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.