International Journal of Molecular Sciences | |
Verification of SNPs Associated with Growth Traits in Two Populations of Farmed Atlantic Salmon | |
Hsin Y. Tsai2  Alastair Hamilton1  Derrick R. Guy1  Alan E. Tinch1  Steve C. Bishop2  Ross D. Houston2  | |
[1] Landcatch Natural Selection Ltd., 15 Beta Centre, Stirling University Innovation Park, Stirling FK9 4NF, UK;The Roslin Institute and Royal (Dick) School of Veterinary Studies, the University of Edinburgh, Midlothian EH25 9RG, UK; | |
关键词:
Atlantic salmon;
growth;
GWAS;
marker-assisted selection;
MAS;
SNP;
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DOI : 10.3390/ijms17010005 | |
来源: mdpi | |
【 摘 要 】
Understanding the relationship between genetic variants and traits of economic importance in aquaculture species is pertinent to selective breeding programmes. High-throughput sequencing technologies have enabled the discovery of large numbers of SNPs in Atlantic salmon, and high density SNP arrays now exist. A previous genome-wide association study (GWAS) using a high density SNP array (132K SNPs) has revealed the polygenic nature of early growth traits in salmon, but has also identified candidate SNPs showing suggestive associations with these traits. The aim of this study was to test the association of the candidate growth-associated SNPs in a separate population of farmed Atlantic salmon to verify their effects. Identifying SNP-trait associations in two populations provides evidence that the associations are true and robust. Using a large cohort (
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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