Structural Elucidation of α-Cyclodextrin-Succinic Acid Pseudo Dodecahydrate: Expanding the Packing Types of α-Cyclodextrin Inclusion Complexes

Crystals

Sofiane Saouane²  Francesca P. A. Fabbiani¹ 

[1] Georg-August-Universität Göttingen, GZG, Abt. Kristallographie, Goldschmidtstr. 1, 37077 Göttingen, Germany

关键词: cyclodextrins;    inclusion complexes;    crystallization;    structural disorder;   

DOI  :  10.3390/cryst6010002

来源: mdpi

【 摘 要 】

This paper reports a new packing type of α-cyclodextrin inclusion complexes, obtained here with succinic acid under low-temperature crystallization conditions. The structure of the 1:1 complex is characterized by heavy disorder of the guest, the solvent, and part of the host. The crystal packing belongs to the known channel-type structure; the basic structural unit is composed of cyclodextrin trimers, as opposed to the known isolated molecular or dimeric constructs, packed along the c-axis. Each trimer is made of crystallographically independent molecules assembled in a stacked vase-like cluster. A multi-temperature single-crystal X-ray diffraction analysis reveals the presence of dynamic disorder.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.