Synthesis of High Valence Silver-Loaded Mesoporous Silica with Strong Antibacterial Properties

International Journal of Environmental Research and Public Health

Chun-Chi Chen¹  Hsin-Hsien Wu¹  Hsin-Yi Huang¹  Chen-Wei Liu¹  Yi-Ning Chen² 

[1] Green Energy and Environment Research Laboratories, Industrial Technology Research Institute, 195 Chung Hsing Road, Chutung, Hsinchu County 31040, Taiwan;;Department of Bioscience Technology, Chung Yuan Christian University, 200 Chung Pei Road, Chung Li District, Taoyuan City 32023, Taiwan

关键词: high valence;    silver;    SBA-15;    antibacterial activity;   

DOI  :  10.3390/ijerph13010099

来源: mdpi

【 摘 要 】

A simple chemical method was developed for preparing high valence silver (Ag)-loaded mesoporous silica (Ag-ethylenediaminetetraacetic acid (EDTA)-SBA-15), which showed strong antibacterial activity. Ag-EDTA-SBA-15 exhibited stronger and more effective antibacterial activity than commercial Ag nanoparticles did, and it offered high stability of high valence silver in the porous matrix and long-lasting antibacterial activity. The synthesized materials were characterized using Fourier transform infrared spectroscopy, powder X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) analysis, and transmission electron microscopy (TEM). Ag existed in both surface complexation and Ag particles. EDTA anchored within a porous structure chelated Ag ions in higher oxidation states and prevented their agglomeration and oxidation reduction. The XRD results showed that most Ag in the Ag-EDTA-SBA-15 existed in higher oxidation states such as Ag(II) and Ag(III). However, the XPS and TEM results showed that Ag easily reduced in lower oxidation states and agglomerated as Ag particles on the exterior layer of the SBA-15.

【 授权许可】

CC BY   
© 2016 by the authors; licensee MDPI, Basel, Switzerland.