Cancers | |
Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells | |
Luciana O. Almeida1  Douglas M. Guimars1  Cristiane H. Squarize1  Rogerio M. Castilho1  | |
[1] Laboratory of Epithelial Biology, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USA; | |
关键词: HNSCC; CSC; cancer initiating cells; spheres; holoclones; meroclones; paraclones; ALDH; BMI-1; histone; | |
DOI : 10.3390/cancers8010007 | |
来源: mdpi | |
【 摘 要 】
Cancer stem cells (CSCs) are a subpopulation of tumor cells endowed with self-renewal properties and the capacity to dynamically adapt to physiological changes that occur in the tumor microenvironment. CSCs play a central role in resistance to therapy and long-term disease recurrence. Better characterization and understanding of the available
【 授权许可】
CC BY
© 2016 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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