Essential thrombocytosis accompanied by coagulation factor XII deficiency: a case report

International Journal of Clinical and Experimental Medicine

Hong Li¹  Chuansheng Zhu¹  Yan Wang¹  Zunsong Wang¹  Kehong Bi¹ 

关键词: Essential thrombocytosis;    coagulation factor XII deficiency;    myeloproliferative disease;    von Willebrand disease;   

DOI  :  

学科分类：医学（综合）

来源: e-Century Publishing Corporation

【 摘 要 】

Essential thrombocytosis (ET) is a type of myeloproliferative neoplasm with clinical manifestations of thrombosis and hemorrhage, the mechanisms of which remains unclear. Some researches indicated that ET is mainly related to the defect of platelet function and the abnormality of coagulation mechanism. A few reports showed that ET accompanied by acquired hemophilia. However, no evidence of ET with coagulation factor XII deficiency has been published. we here report a case of ET accompanied with coagulation factor XII deficiency, which had clinically significant bleeding tendency.

【 授权许可】

Unknown