A rare der(Y)t(Y;1)(q12;q12) in a patient with post-polycythemic myelofibrosis: a case report

American Journal of Blood Research

Junya Okita¹  Naonori Harada¹  Shuichiro Okamoto¹  Yoshio Furukawa¹  Osami Takeda¹  Masahiro Manabe¹  Takeo Kumura¹  Hirofumi Nakano¹  Atsuko Mugitani¹  Yasutaka Aoyama¹  Tadanobu Ohta¹  Teruhito Takakuwa¹ 

关键词: Post-polycythemic myelofibrosis;    der(Y)t(Y;    1)(q12;    q12);    chromosomal abnormality;   

DOI  :  

学科分类：血液学

来源: e-Century Publishing Corporation

【 摘 要 】

We describe a case of post-polycythemic myelofibrosis harboring der(Y)t(Y;1)(q12;q12). The patient was a 69-year-old man and was initially diagnosed with polycythemia vera. During the clinical course of his condition, the polycythemia developed into myelofibrosis. Chromosome analysis detected der(Y)t(Y;1)(q12;q12). We discuss the association between der(Y)t(Y;1)(q11~12;q12~21) and tumorigenesis along with a review of literature.

【 授权许可】

Unknown