Biomarkers for bladder cancer management: present and future

American Journal of Clinical and Experimental Urology

Fei Ye¹  Paolo Boffetta¹  Carlos Cordon-Cardo¹  Li Wang¹  Matthew D Galsky¹  Russell McBride¹  Jun Zhu¹  Mireia Castillo-Martin¹  David Y Zhang¹ 

关键词: Bladder cancer;    biomarkers;    disparities;   

DOI  :  

学科分类：医学（综合）

来源: e-Century Publishing Corporation

【 摘 要 】

Accurate and sensitive detection of bladder cancer is critical to diagnose this deadly disease at an early stage, estimate prognosis, predict response to treatment, and monitor recurrence. In past years, laboratory diagnosis and surveillance of urinary bladder cancer have improved significantly. Although urine cytology remains the gold standard test, many new urinary biomarkers have been identified. Furthermore, recent advances in genomic studies of bladder cancer have helped to refine our understanding of the pathogenesis of the disease, the biological basis for outcome disparities, and to inform more efficient treatment and surveillance strategies. In this article, the established diagnostic tests, newly identified biomarkers and genomic landscape of bladder cancer will be reviewed.

【 授权许可】

Unknown