The Effects of Lidocaine and Mefenamic Acid on Post-Episiotomy Pain: A Comparative Study

lranian journal of Clinical Infectious Diseases

Masoumeh Delaram¹  Lobat Jafar Zadeh²  Sahand Shams³ 

[1] Faculty of Nursing and Midwifery, Shahrekord University of Medical Sciences, Shahrekord, IR Iran;Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, IR Iran;Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, IR Iran

关键词: Lidocaine;    Mefenamic Acid;    Post-Episiotomy Pain;   

DOI  :  10.17795/semj36286

学科分类：基础医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

Background:Mostwomensufferpainfollowinganepisiotomyandoralnon-steroidalanti-inflammatorydrugsarecommonlyusedforpainrelief.Duetothegastrointestinalsideeffectsoforaldrugs,itseemsthatwomenaremoreacceptingoftopicalmedicationsforpainrelief.Objectives:Therefore,theaimofthisstudywastocomparetheeffectsoflidocaineandmefenamicacidonpost-episiotomypain.PatientsandMethods:Thisclinicaltrialwascarriedoutin2011.Itinvolvedsixtywomenwithsingletonpregnancywhoweregivenanepisiotomyat38to42weeksofgestation.Theparticipantswererandomlydividedintotwogroups.Onegroupreceived2%lidocainecream(n=30),whiletheothergroupreceived250mgofmefenamicacid(n=30).Thedatawerecollectedviaaquestionnaireandavisualanalogscale.Painintensitywascomparedfromthefirstcomplaintbythemotherandat6,12,and24hoursafterthedeliveryinbothgroups.ThedatawereanalyzedusingSPSS(version16),thet-test,andthepairedt-test,andaPvalueoflessthan0.05wasconsideredsignificant.Results:Themeanintensityofpainatthefirstcompliantwas4.92±1.9inthelidocainegroupand4.90±1.5inthemefenamicacidgroup,andthedifferencewasnotstatisticallysignificant(P=0.20).Additionally,therewasnosignificantdifferenceinthemeanintensityofpost-episiotomypainbetweenthetwogroupsat6(P=0.05),12(P=0.36),and24(P=0.98)hoursafterchildbirth.Conclusions:Theeffectsofthelidocainecreamandmefenamicacidweresimilarintermsofthereliefofpost-episiotomypain.Lidocainecreamthereforerepresentsagoodalternativetomefenamicacid,whichiscommonlyusedtoreducepainfollowinganepisiotomy,especiallyinwomenwhoarebreastfeedingandwhowishtoavoidoralanalgesicdrugsbeingsecretedintheirmilk.

【 授权许可】

Unknown