Remedial Effect of Boswellia Serrata on Thermal Burn Injuries

lranian journal of Clinical Infectious Diseases

Najmeh Sahinfard¹  Rasool Arami¹  Azar Baradaran⁴  Parto Nasri⁴  Mortaza Rafieian⁵  Abdolrasool Namjoo²  Hedayatollah Shirzad¹  Hamid Nasri³  Mahmoud Rafieian-Kopaei¹ 

[1] Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, IR Iran;Pathology Department, Islamic Azad University, Shahrekord Branch, Shahrekord, IR Iran;Department of Nephrology, Isfahan University of Medical Sciences, Isfahan, IR Iran;Department of Pathology, Isfahan University of Medical Sciences, Isfahan, IR Iran;Isfahan Governor Office, Isfahan, IR Iran

关键词: Mice;    Inbred BALB/c;    Boswellia;    Burns;    Wound Healing;   

DOI  :  10.17795/semj26239

学科分类：基础医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

Background:Ithasbeenshownthatinflammationandinsufficientbloodvesselformationdelaywoundhealing,whereasBoswelliaserrata,besidesanti-inflammatoryactivity,increasesbloodvesselformation.Objectives:ThisstudywasperformedtoinvestigatetheeffectofBoswelliaserratainpromotingburninjurieshealinginBALB/cmice.MaterialsandMethods:Inthisexperimentalstudy,aburnwoundwascreatedbyplacinga1.5cm2hotplateonthebackofanimals.Fiftyfourmiceweredesignatedinfourequalgroups,counting14each.ThreegroupsofanimalsweretreatedwithBoswellia2%,silversulfadiazineandvaselinetwotimesperdayfor21days.Thefourthgrouprepresentedthecontrolgroup.Thetotalpercentageofwoundhealingandtimerequiredforcompletehealingwereevaluatedandcomparedbetweengroups,usingtheANOVAtest.Results:ResultsshowedthattheeffectofBoswelliaonwoundhealingwasstatisticallysignificantcomparedtothecontrolgroup(Plt;0.01).Conclusions:Boswelliaserrataisclearlyeffectiveforburninjurieshealingandmightbeusedinpatientswithburnwound.

【 授权许可】

Unknown