Seroprevalence and Co-Infection of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus in Nigeria.

lranian journal of Clinical Infectious Diseases

JD Mawak²  YA Agabi¹  AB Atseye⁴  H Zakeri¹  N Dashe³ 

[1] Lecturer, Department of Microbiology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria;Reader, Department of Microbiology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria;Reader, Department of Microbiology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria Lecturer, Department of Medical Microbiology, Faculty of Medical Sciences, University of Jos, P.M.B 2084, Jos, Nigeria;Reader, Department of Microbiology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria Lecturer, Department of Medical Microbiology, Faculty of Medical Sciences, University of Jos, P.M.B 2084, Jos, Nigeria Graduate Student, Department of Science Laboratory Technology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria

关键词: Herpes Simplex Virus Type 2;    Human Immunodeficiency Virus;    Pankshin;    Plateau State;    Nigeria.;   

DOI  :  10.17795/semj20506

学科分类：基础医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

Background:Herpessimplexvirustype2(HSV-2)isasexuallytransmittedvirusthatisthemostcommoncauseofgenitalulcerationworldwide.TheincreasingevidencethatHSV-2infectioncouldsignificantlyenhancetheratesofsexualtransmissionandacquisitionofhu-manimmunodeficiencyvirus(HIV)indevelopingcountriesinformedourdesignofthisstudy.Objective:Todeterminetheseroprevalenceandco-infectionofHSV-2andHIVandtoevaluatetheirassociationwithdemographicfactorsamongadults(≥15yrs)inPankshin.Methods:Onehundredandeightybloodsampleswerecollectedfromadults,age≥15yearsfromTownClinicPankshinandGeneralhospitalBillangShippanginPankshinLocalGovern-mentAreaofPlateauState.DetermineTMandStatpakrapidtestkitswereusedtoscreenthecollectedsamplesforantibodiestoHIV.TheseroprevalenceofHSV-2wasdeterminedusingDiaproHSV-2typespecificELISAKitaccordingtothemanufacturer’sinstructionalmanual.Results:TheestimatedprevalenceofHSV-2was24.4%anditwashigheramongwomen(26.09%)thanamongmen(21.53%).ThatofHIVwas19.49%;menhadaprevalencerateof4.69%whilethatofwomenwas5.22%.Conclusion:HSV-2antibodieswerefrequentinthestudygroup,genitalherpeswasnotre-portedbytheHSV-2positivesubjects,indicatinglowawarenessoftheHSV-2infection.TheprevalenceofHIVhoweverwasnotthatsignificant.Thepercentageofco-infectionwas2.8%.

【 授权许可】

Unknown