lranian journal of Clinical Infectious Diseases | |
Seroprevalence and Co-Infection of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus in Nigeria. | |
JD Mawak2  YA Agabi1  AB Atseye4  H Zakeri1  N Dashe3  | |
[1] Lecturer, Department of Microbiology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria;Reader, Department of Microbiology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria;Reader, Department of Microbiology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria Lecturer, Department of Medical Microbiology, Faculty of Medical Sciences, University of Jos, P.M.B 2084, Jos, Nigeria;Reader, Department of Microbiology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria Lecturer, Department of Medical Microbiology, Faculty of Medical Sciences, University of Jos, P.M.B 2084, Jos, Nigeria Graduate Student, Department of Science Laboratory Technology, Faculty of Natural Sciences, University of Jos, P.M.B 2084, Jos, Nigeria | |
关键词: Herpes Simplex Virus Type 2; Human Immunodeficiency Virus; Pankshin; Plateau State; Nigeria.; | |
DOI : 10.17795/semj20506 | |
学科分类:基础医学 | |
来源: Shiraz University of Medical Sciences | |
【 摘 要 】
Background:Herpessimplexvirustype2(HSV-2)isasexuallytransmittedvirusthatisthemostcommoncauseofgenitalulcerationworldwide.TheincreasingevidencethatHSV-2infectioncouldsignificantlyenhancetheratesofsexualtransmissionandacquisitionofhu-manimmunodeficiencyvirus(HIV)indevelopingcountriesinformedourdesignofthisstudy.Objective:Todeterminetheseroprevalenceandco-infectionofHSV-2andHIVandtoevaluatetheirassociationwithdemographicfactorsamongadults(≥15yrs)inPankshin.Methods:Onehundredandeightybloodsampleswerecollectedfromadults,age≥15yearsfromTownClinicPankshinandGeneralhospitalBillangShippanginPankshinLocalGovern-mentAreaofPlateauState.DetermineTMandStatpakrapidtestkitswereusedtoscreenthecollectedsamplesforantibodiestoHIV.TheseroprevalenceofHSV-2wasdeterminedusingDiaproHSV-2typespecificELISAKitaccordingtothemanufacturer’sinstructionalmanual.Results:TheestimatedprevalenceofHSV-2was24.4%anditwashigheramongwomen(26.09%)thanamongmen(21.53%).ThatofHIVwas19.49%;menhadaprevalencerateof4.69%whilethatofwomenwas5.22%.Conclusion:HSV-2antibodieswerefrequentinthestudygroup,genitalherpeswasnotre-portedbytheHSV-2positivesubjects,indicatinglowawarenessoftheHSV-2infection.TheprevalenceofHIVhoweverwasnotthatsignificant.Thepercentageofco-infectionwas2.8%.
【 授权许可】
Unknown
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