Transfer of Amoxicillin Resistance Gene Among Bacterial Isolates From Sputum of Pneumonia Patients Attending the University of Benin Teaching Hospital, Benin City, Nigeria.

lranian journal of Clinical Infectious Diseases

E.E. Akortha²  H.S.A. Aluyi¹  K.E. Enerrijiofi² 

[1] Department of Microbiology, Benson Idahosa University, Benin city.;Department of Microbiology, Faculty of Life Sciences, University of Benin, Benin City,

关键词: Amoxicillin resistance;    pneumonia;    gene transfer;    plasmid;    curing;    conjugation;    sputum;   

DOI  :  10.17795/semj20459

学科分类：基础医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

Abstract::Atotalof160sputumsampleswereobtainedfrompneumoniapatients(1–30years)attendingtheUniversityofBeninTeachingHospital,BeninCity.ThemicroorganismsencounteredincludedStreptococcusviridians,Staphylococcusaureus,Klebsiellapneumoniae,MoraxellacatarrhalisandStaphylococcusspecies.S.viridanswashighestinoccurrence(51.5%)andStaphylococcusspp.wastheleast(2.9%).Theirantibioticresistancepatternrevealedthatstreptomycinhadthehighestactivity(94.1%)andgentamycintheleast(23.8%).Amoxicillinresistancegene(amxr)wasdetectedin89(88.1%)outofthetotalisolates.Whentheseresistantisolatesweresubjectedtocuringusing10%sodiumdodecylsulfate,73(82.0%)losttheirresistancegenes.Anaveragetransferrateof53.88%and33.59%wereobtainedforintraspeciesandintergenerictransferofamxrgenerespectively.Intraspeciesgenetransferratewassignificantlyhigherthanintergenericatp#60;0.001,usingthechi–squaregoodnessoffittestforstatisticalanalysis.

【 授权许可】

Unknown