Intravenous Drug Use: the Predominant Risk Factors for Hepatitis C Virus Infection

lranian journal of Clinical Infectious Diseases

A Najafi³  F Fallahian²  SM Alavian¹ 

[1] Professor, Baqiyatallah Research Center for Gastroenterology and Liver Disease, Baqiyatallah University of Medical Sciences, Tehran, Iran.;Sina Hospital, Tehran University of Medical Sciences, Imam Khomeini St., Tehran, Iran,Clinical Fellow, Intensive Care Unit;Associate Professor, Department of Anesthesiology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

关键词: Hepatitis C virus;    Global prevalence;    Transmission;    intravenous drug use;   

DOI  :  10.17795/semj20443

学科分类：基础医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

ThismanuscriptprovidesaliteraturereviewofprevalenceandroutesofhepatitisCvirustransmission,andpreventionmethodsregardingitsprevalenceindifferentpopulations.ThereisagreatdifferenceinthefrequencyofhepatitisCvirusinfectionofgeneralpopulationversusinjectiondrugusers.Evenindevelopingcountrieswithunsafetherapeuticinjectionsandcontaminatedblood,therateofdiseaseishigherininjectingdrugusere.AliteraturereviewofpublishedscientificreportsonHCVepidemiology,prevalence,anditsrelationtoaddictioninsomecountrieswasperformed.WhiledifferentepidemiologicpatternsofHCVinfectionexistwithseroprevalenceof0.4%to1.1%and9.6%to20%ingeneralpopulationinNorthAmericaandsomecountriesofNorthAfrica;respectively,thefrequencyofHCVinfectionininjectiondrugusersis48%to90%.InjectiondruguseseemsthemostimportantworldwideriskfactorforhepatitisCvirusinfection.Substanceabuse,HCVinfectionandmentalillnessfrequentlycoexistandcomplicateHCVtreatment.Implementingeffectivemeasuresforpreventinginjectingdrugusebyeffectivedrugeducationprogramsinschool,researchinbehavioral/environmentaladdictionpredispositions,implementstrictdrugabusepolicy,regularestimationofaddictionpatterns,andtomodelpreventionapproachesaccordingtoeverycertainsituationisnecessary.

【 授权许可】

Unknown