Comparison Spirometry Test with Related Factors on Pulmonary Complications in Exposed Persons to Mustard Gas

lranian journal of Clinical Infectious Diseases

N Nozari¹ 

[1] Assistant Professor, Section of Pulmonology, Department of Internal Me-dine, Jondishahpor University of Medical Sciences, Ahwaz, Iran

关键词: Mustard gas;    Prevalence rate;    Spirometry test;    Pulmonary complications;   

DOI  :  10.17795/semj20375

学科分类：基础医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

Backgroundandobjective:Duringthe8yearIraq-Iranwar(1980-1988)chemicalweaponswerefrequentlyusedagainstIran.Theaimofthisstudywastodeterminesomerelatedfactorsbesidesaspirometrytestthatcanpredictandevaluatelatepulmonaryeffectsonpersonsexposedtomustardgas.Method:Inacrosssectionalstudyof500mustardgasexposedpersons,wemeasuredspi-rometricparameterswithanassessmentoftheirrelationshipwithrelatedfactorsincludingrespiratorysymptomsandsigns,age,numberofexposureepisodes,lengthofpostfirstexposuretimeanduseofprotectivemaskattimeofexposure.Findings:Of500exposedpersonswiththemeanageof(45.6±6.5y),91.6%(n=458)hadlungSymptoms,dyspnea88.2%(n=441,productivecough36.2%(n=181),drycough29.4%(n=147),haemopthesis18.6%(n=93),and8.2%(n=41)hadpositivefindingsofthefollowinginphysicalexamination:wheezing6.6%(n=33),ronchi1.2%(n=6),andcrackles0.4%(n=2).Inaspirometrytest,52.4%(n=262)hadadysfunction.Ofthese,27.2%(n=136)showedobstructivepattern,and25.2%(n=126)showedarestrictivepattern.Prevalenceofmildlungrestrictivewas94.44%(n=119)andmildobstructivepat-ternwas36.03%(n=49).Formoderatelungrestrictivepatternprevalencewas5.56%(n=7)andmoderateobstructivepatternwas33.09%(n=45).Formoderatetoseverelungob-structivepatternprevalencewas11.76%(n=16),andofseverelungobstructivepatternprevalencewas19.12%(n=26).Prevalenceofdysfunctionspirometrytestincreasedwithincreasingthelengthofpostfirstexposuretimeandnouseofprotectivemaskatthetimeofexposure.Therewasn'tanystatisticalsignificantrelationshipbetweenrespiratorysymptomsandsigns,thenumberofexposureepisodes,andagewithdysfunctionspirometrytest.Conclusion:Themostcommontypeofdysfunctionspirometrytestisobstructiveandthenrestrictivepatterninmustardgasexposedpersons.Thefactorscontributingtotheincreaseofprevalenceofdysfunctionspirometrytestincludeincreasingthelengthofpostfirstexpo-suretimeandnouseofprotectivemask

【 授权许可】

Unknown