Anti-hyperlipidaemic Effects of an Essential Oil of Melissa officinalis. L in Cholesterol-fed Rabbits

Journal of Applied Biological Sciences

Mohammadmehdi HADIPOUR¹  Isaac KARIMI¹  Hossein HAYATGHEYBI¹  Amir DADYAN¹  Másume YOUSEFI¹  Mostafa RAZMJO¹ 

关键词: Lemon balm;    Hyperlipidaemia;    Essential oil;    Cholesterol;    Triglycerides;   

DOI  :  

学科分类：生物科学（综合）

来源: Nobel Bilim ve Arasirma Merkezi/Nobel Science and Research Cente

【 摘 要 】

Theaimofthisstudywastoinvestigatetheeffectsofanessentialoil(EO)ofatraditionalherb;Melissaofficinalis(MO),onthelipidprofileofrabbitsfedacholesterol-richdiet(HC).Twentyrabbitsweredividedintofourgroups(n=5foreach):Normalcontrol(NC)whichfedastandarddietandthreecholesterol-fedgroups:HC,HC+1%MO,andHC+3%MOgroupswhichreceived0%,1%,and3%EO,respectivelyforfourweeks.Bloodsampleswerecollectedonday0andthenatweeks1,2,3,and4todeterminethelevelsoftotalserumcholesterol(TC),highdensitylipoprotein-cholesterol(HDL-C),lowdensitylipoprotein-cholesterol(LDL-C),verylowdensitylipoprotein-cholesterol(VLDL-C),triglycerides(TGs)andatherogenicindex(AI).Therewerenosignificantdifferencesinbodyweightgainandfoodintakeinallgroups.TheHCapparentlyraisedtheTC,LDL-C,VLDL-C,HDL-CandTGswithoutsignificantaccrualeffectonAI.IncomparisontoNCgroup,EOinbothHC+1%MOandHC+3%MOgroupssignificantlydecreasedserumlipidandlipoproteinlevelwhereasnosignificanteffectonAIwasobserved.ItcanbeconcludedthatEOextractedfromMOleavescontributestoalipid-loweringactionincholesterol-fedrabbits.

【 授权许可】

Unknown