Acidogenicity and acid tolerance ofStreptococcus oralisandStreptococcus mitisisolated from plaque of healthy and incipient caries teeth

Journal of Oral Microbiology

Derek R. Blanchette¹  Jeffrey A. Banas¹  Deborah V. Dawson¹  Hongjie Gu¹  Ryan Frost¹  David R. Drake¹  Grant McCaulley¹  Steven M. Levy²  Min Zhu¹ 

[1] University of Iowa College of Dentistry;University of Iowa College of Dentistry

关键词: Dental Plaque;    Mutans Streptococci;    Cariogenicity;    Oral Microflora;    Acidogenicity;    Acid Tolerance;   

DOI  :  

来源: Co-Action Publishing

【 摘 要 】

Background:Non-mutanslowpHoralstreptococciarepostulatedtocontributetocariesetiology.Objective:ThisstudywasundertakentoinvestigatewhethertheacidogenicityandacidtoleranceofclinicalstrainsofStreptococcusoralisandStreptococcusmitiscorrelatewithhealthorearly-stageenamelcaries.Design:S.oralisandS.mitiswereisolatedfromplaquesamplestakenfromtheocclusalsurfacesofsecondmolarssampledattwodifferentvisits4yearsapart.AllsitesweresoundatVisit1;subjectsweresegregatedintooneofthreegroupsbasedonthestatusofthesiteatVisit2andcarieselsewhereinthedentition.StrainsofS.oralisandS.mitiswereevaluatedforacidogenicityandacidtolerance,andtheresultscorrelatedwiththeclinicalstatusofthesitesfromwhichtheywereisolated.Mutansstreptococci(MS)isolatedfromtheplaquesampleswerealsoquantified,andthepresenceorabsenceofgrowthonpH5.5mediaoronmediaselectiveforbifidobacteriawasrecorded.Results:NosignificantpositivecorrelationswerefoundbetweentheacidogenicitypropertiesoftheS.oralisandS.mitisclonesandcariesateithervisit.SimilarresultswereobtainedforacidtoleranceofS.oralisclonesbutwereinconclusiveforS.mitisclones.AstatisticallysignificantpositivecorrelationbetweenMSlevelsandcaries(orfuturecaries)wasevidentatbothvisits,buttherewerenostatisticalcorrelationswiththegrowthonpH5.5mediaormediaselectiveforbifidobacteria.Conclusions:ThelowpHpotentiallikelyvariesconsiderablyamongoralstreptococcalspeciesandisleastlikelytobefoundamongstrainsofS.mitis.Accordingly,theconceptandconstitutionof‘lowpHstreptococci’mayneedtobere-evaluated.Keywords:dentalplaque;mutansstreptococci;cariogenicity;oralmicrobiota;acidogenicity;acidtolerance(Published:26October2016)Citation:JournalofOralMicrobiology2016,8:32940-http://dx.doi.org/10.3402/jom.v8.32940

【 授权许可】

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