Investigation of Gas Redistribution in Doubly Bifurcated Respiratory Channel of Human Lung

Journal of Biomechanical Science and Engineering

Tomonori YAMAMOTO²  Mahtab Uddin AHMMED²  Katsuya IWAZAKI²  Hiroyuki HIRAHARA¹ 

[1] Division of Human Support and Production Sciences, Saitama University;Graduate School of Science and Engineering, Saitama University

关键词: Human Lung;    Respiratory Region;    HFOV;    Particle Image Velocimetry;    Pendelluft;    Alveoli;    Air Trajectory;   

DOI  :  10.1299/jbse.6.1

来源: Japan Society of Mechanical Engineers

【 摘 要 】

References(28)Cited-By(1)An oscillatory flow in human lung was investigated with a real scale model channel experimentally. One objective of the present study is to clarify the gas exchange mechanism in the peripheral channel, e.g. from the 18-th to 20-th generations, which are the leading region of gas exchanges. The second object is the inspection of the flow convection under the HFOV (high frequency oscillatory ventilation) condition. The experiment was carried out with a real scale two-dimensional model of airway, instead of using a similarity model, in order to take into account the practical condition of HFOV. The velocity profiles were obtained from ensemble mean measurements and the air trajectories were demonstrated with the ensemble mean velocities in the test section. It was confirmed that the air trajectories of expiration were deviated from those of inspiration in the intermediate zone of our channel. It was predicted that a convective flow mixing might be took place depending on the geometric configuration and the asymmetric compliance ratios of the bronchioles.

【 授权许可】

Unknown