Fabrications, Applications and Challenges of Solid-State Nanopores: A Mini Review

Nanomaterials and Nanotechnology

Weiwei Cui¹  Zifan Tang¹  Hao Zhang¹  Xuexin Duan¹  Daihua Zhang¹  Wei Pang¹ 

关键词: Nanopore;    Fabrication;    Molecular Translocation;    DNA Sequencing Protein Detection;   

DOI  :  10.5772/64015

来源: InTech

【 摘 要 】

Nanopore sensors are expected to be one of the most promising next generation sequencing technologies, with label-free, amplification-free and high-throughput features, as well as rapid detections and low cost. Solid-state nanopores have been widely explored due to their diverse fabrication methods and CMOS compatibility. Here, we highlight the fabrication methods of solid-state nanopores, including the direct opening and the tuning methods. In addition, molecular translocation developments, DNA sequencing and protein detections are summarized. Finally, the latest progress relating to solid-state nanopores is discussed, which helps to offer a comprehensive understanding of the current situation for solid-state nanopore sensors.

【 授权许可】

Unknown