期刊论文详细信息
Nanomaterials and Nanotechnology
Enhancement of antioxidant and skin moisturizing effects of olive oil by incorporation into microemulsions
Wantida Chaiyana1  Kanokwan Kiattisin1  Pimporn Leelapornpisid1  Rungsinee Phongpradist1 
关键词: Antioxidant;    moisturizing;    microemulsion;    olive oil;    Olea europaea;    cosmetics;    drug delivery system;   
DOI  :  10.1177/1847980416669488
来源: InTech
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【 摘 要 】

The aims of the present study were to develop olive oil microemulsions and characterize their antioxidant and skin moisturizing properties. The acid, iodine, and saponification values of olive oil were 0.38 ± 0.01 mg potassium hydroxide/g, 88.2 ± 5.9 mg iodine/g, and 192.2 ± 1.4 mg potassium hydroxide/g, respectively. Pseudoternary phase diagrams, constructed using the water titration method, produced suitable microemulsions: microemulsion 1 (10% olive oil, 64% Tween 85, 16% propylene glycol, and 10% water) and microemulsion 2 (10% olive oil, 64% Tween 85, 16% ethanol, and 10% water). Microemulsions 1 and 2 exhibited Newtonian flow behavior with internal droplet sizes of 443.60 ± 27.66 nm and 139.37 ± 12.15 nm, respectively. Their in vitro antioxidant and skin moisturizing properties were investigated in comparison with native olive oil. Microemulsion 2 possessed the highest significant antioxidant effect (p < 0.05) giving half maximal inhibitory concentration values in radical-scavenging activity against...

【 授权许可】

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