Identification of Proteins Involved in Cytokinesis of Dictyostelium

Cell Structure and Function

Hiroyuki Adachi¹ 

[1] Department of Biotechnology, Graduate School of Agricultural and Life Sciences, University of Tokyo

关键词: cytokinesis;    Dictyostelium;    REMI;    gene targeting;    IQGAP;    GAPA;   

DOI  :  10.1247/csf.26.571

学科分类：分子生物学，细胞生物学和基因

来源: Japan Society for Cell Biology

【 摘 要 】

References(33)Cited-By(2)Dictyostelium is one of the model systems of choice for studying the cytokinesis of animal-type cells. Two types of cytokinesis mutants have been used to identify proteins involved in the cytokinesis of Dictyostelium: (1) type I, the mutant cells grow on substrates to produce giant multinucleate cells; (2) type II, the mutant cells divide nearly normally on substrates, but are unable to divide at all and get highly multinucleate in suspension culture. These two mutant types might correspond to the myosin II-independent and myosin II-including cytokinesis mechanisms, respectively.

【 授权许可】

Unknown