Vasa Homolog Genes in Mammalian Germ Cell Development

Cell Structure and Function

Toshiaki Noce¹  Naoki Tsunekawa¹  Shino Okamoto-Ito¹ 

[1] Laboratory of Reproductive Biology, Mitsubishi Kasei Institute of Life Sciences

关键词: primordial germ cell (PGC);    vasa;    spermatogenesis;    chromatoid body;   

DOI  :  10.1247/csf.26.131

学科分类：分子生物学，细胞生物学和基因

来源: Japan Society for Cell Biology

【 摘 要 】

References(35)Cited-By(80)Many vasa homologue genes to Drosophila vasa have been isolated in various animal species. They provide specific molecular probes to analyze the establishment and the differentiation of germ cell lineage. In mammals, the expression of VASA protein becomes detectable in PGCs at the late migrating stage. Interestingly, during spermatogenesis the intracellular localization of VASA protein is closely associated with the chromatoid body.

【 授权许可】

Unknown