The Role of Dynein in Microtubule-based Motility

Cell Structure and Function

I.R. Gibbons¹ 

[1] Pacific Biomedical Research Center, University of Hawaii

关键词: microtubule;    actin stress fiber;    rho;    GTP binding protein;    signal transduction;   

DOI  :  10.1247/csf.21.331

学科分类：分子生物学，细胞生物学和基因

来源: Japan Society for Cell Biology

【 摘 要 】

References(59)Cited-By(20)Dyneins are high molecular weight ATPases that function as microtubule-based molecular motors. The axonemal dyneins, discovered 30 years ago, are responsible for the beating movement of cilia and sperm flagella, which they generate by producing sliding between adjacent microtubules. Cytoplasmic dynein, more recently discovered, is involved in diverse activities, including intracellular transport, nuclear migration, and the orientation of the cell spindle at mitosis.

【 授权许可】

Unknown