Configuration Optimization and Mass Transfer in a Dual-Impeller Bioreactor

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Liangzhu Zu¹  Chao Yang²  Zai-Sha Mao²  Hongbao Zhou²  Xiangyang Li²  Shifang Yang² 

[1] State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing Tech University;Key Laboratory of Green Process and Engineering, National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences

关键词: Bioreactors;    Leaching;    Low Shear;    Gas–Liquid–Solid;    Mass Transfer;    Mixing;   

DOI  :  10.1252/jcej.14we018

来源: Maruzen Company Ltd

【 摘 要 】

References(28)The bioreactor configuration including a dual-impeller combination, spacing between the impellers, and the diameter of the ring sparger is optimized based on solid suspension (Njsg) and gas dispersion (Nf and kLa) in this work. Then, the solid suspension and gas dispersion performance in this optimized bioreactor are systematically studied. It is found that a smaller sparger (Ds/T=0.32) achieves better performance in gas dispersion. A pitched-blade disc turbine down-pumping (PDTD) as a bottom impeller achieves the lowest Njsg value, and has lower Nf value compared with PBTD (pitched blade turbine down-pumping) and TBHA (three-bladed helical agitator). Techmix 335 hydrofoil impeller down-pumping (TXD) as an upper impeller provides higher kLa values. TXD+PDTD are more suitable for the requirements of a bioreactor. kLa decreases slightly with increasing solid loading, which is beneficial to good gas dispersion in such bioleaching reactors with higher solid loadings (>20 wt%).

【 授权许可】

Unknown