Theoretical and Experimental Evaluation for Blood Pressure Drop and Oxygen Transfer Rate in Outside Blood Flow Membrane Oxygenator

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Koichiro Tahara²  Masayuki Nakamura¹  Katsuyuki Kuwana²  Noriaki Matsuda¹  Kiyotaka Sakai¹ 

[1] Chemical Engineering Department, Waseda University;Senko Medical Instrument Mfg. Co. Ltd.

关键词: Membrane Oxygenator;    Simulation Analysis;    Darcy’s Law;    Blood Pressure Drop;    Oxygen Transfer Rate;   

DOI  :  10.1252/jcej.32.752

来源: Maruzen Company Ltd

【 摘 要 】

References(10)Cited-By(9)An outside blood flow membrane oxygenator with an optimum blood flow pattern is developed by a trial and error method where large cost and long time are spent. We modeled the blood flow in the membrane oxygenator as the flow of low Reynolds number in a porous media and evaluated blood pressure drop and oxygen transfer rate using Darcy’s law. Governing equations are solved by the finite element method. Theoretical blood flow patterns agree well with visualized flow patterns obtained by X-ray computed tomography. Calculated values for blood pressure drop and oxygen transfer rate also agree with experimental data. Optimum structure parameters of the membrane oxygenator can hence be determined by simulation analysis.

【 授权许可】

Unknown