Effect of Axial Dispersion on the Evaluation of Enantiomeric Ratio by a Fixed-Bed Reactor

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Jau-Yann Wu¹ 

[1] Department of Chemical Engineering, I-Shou University

关键词: Enantioselectivity;    Chromatographic Reactor;    Axial Dispersion;    Transient Response;   

DOI  :  10.1252/jcej.31.999

来源: Maruzen Company Ltd

【 摘 要 】

References(10)An earlier investigation has presented a novel procedure in the chromatographic reactor, capable of efficiently determining the enantioselectivity of the enzyme for a biocatalyzed process. In this work, a mathematical model including the effect of axial dispersion is formulated to describe the transient behavior of the fixed-bed used to evaluate the enantiomeric ratio. A valuable relationship among the enantioselectivity, Pèclet number, and transient responses at the exit of reactor is also established through the theoretical analysis. In addition, a relation is proposed to evaluate the significance of axial dispersion in the fixed-bed, allowing us to apply this criterion to assess the necessity of further studying the Pèclet number.

【 授权许可】

Unknown