Macromolecule Rejection with Compressible and Incompressible Cake Layer Formed in Crossflow Microfiltration

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Shin-ichi Nakao¹  Shoji Kimura¹  Takahiro Kawakatsu¹ 

[1] Department of Chemical Engineering, University of Tokyo

关键词: Membrane Separation;    Crossflow Microfiltration;    Cake Compression;    Blocking Resistance;    Saccharomyces cerevisiae;    Polymethyl Methacrylate;    Macromolecule Rejection;    Bovine Serum Albumin;    Dextran;    Dynamic Membrane;   

DOI  :  10.1252/jcej.26.656

来源: Maruzen Company Ltd

【 摘 要 】

References(11)Cited-By(7)In crossfiow microfiltration (CMF) of a suspension of Saccharomyces cerevisiae, a dense layer called a “dynamic membrane” was formed with elastic compression at the interface of the membrane surface and the cake layer, and was found to reject bovine serum albumin (BSA) and Dextran T70 (T70). This macromolecule rejection corresponded to the blocking resistance (Rb), and was dependent on the actual surface pore size (dm), the particle size in suspension (dp) and the particle compressibility. With S. cerevisiae, when dm at 0.5 μm was about one-tenth of dp (2–5 μm), the T70 rejection rate increased to 80% even if dm was large compared to the size of T70. The membrane surface was observed with scanning electron microscopy and it was confirmed that a dense layer with compressed cells and biopolymers surrounding the cell was formed on the surface. On the other hand, the T70 rejection was not observed with the cake layer of polymethyl methacrylate particles (dp: 0.8 μm) because the particle was incompressible and no dense layer was formed.

【 授权许可】

Unknown