Case Report: PTHrP Related Hypercalcemia in Diffuse Large B-cell Lymphoma

The Medicine Forum

Mehta, MD, Ankita¹  Caruso, MD, Evan² 

[1] Thomas Jefferson University HospitalThomas Jefferson University HospitalThomas Jefferson University Hospital;Thomas Jefferson UniversityThomas Jefferson UniversityThomas Jefferson University

关键词: Case Report: PTHrP Related Hypercalcemia in Diffuse Large B-cell Lymphoma;    The Medicine Forum;    Thomas Jefferson University Hospital;    Internal Medicine Program;    oncology;   

DOI  :  

学科分类：医学（综合）

来源: Thomas Jefferson University

【 摘 要 】

INTRODUCTION Hypercalcemia is commonly associated with solid tumor malignancies, but less often with hematologic malignancies. When present in hematologic malignancies, hypercalcemia is often secondary to overproduction of Vitamin D from the tumor cells. Very few cases with parathyroid hormone related peptide (PTHrP) induced hypercalcemia in B-cell lymphomas have been reported. Here we present a 44 year old male with a history of chronic lymphoctic leukemia who presented with hypercalcemia and an elevated PTHrP, found to have a transformation to Diffuse Large B-cell Lymphoma (DLBCL).

【 授权许可】

Unknown