Bacteriological profile and sensitivity pattern of microorganisms causing Urinary Tract Infection at a tertiary care center in eastern Uttar Pradesh

International Journal of Biomedical and Advance Research

Ruchi Mishra¹  Jayesh Pandey¹  Amresh Kumar Singh¹  Kusum Jasuja¹ 

关键词: Urinary Tract Infections (UTI);    uropathogens;    Antimicrobial susceptibility pattern.;   

DOI  :  10.7439/ijbar.v7i6.3366

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Introduction:Urinary tract infection (UTI) is one of the most common infections worldwide, and the pattern of antimicrobial susceptibility varies widely in different regions depending on the antibiotic policies. Aim:To know the bacteriological profile of UTIs and the antibiogram of uropathogens in eastern Uttar Pradesh. Material and Methods:This study was prospective and conducted at tertiary care center in one year study duration (2015). All the patients clinically suspected of having UTI were enrolled, their culture and sensitivity was performed as per standard protocol, irrespective of age, sex, indoor/outdoor and associated illnesses. Results:In a total of 2217 patients, 967 (43.61 %) were positive for uropathogen by culture, and positivity in female was high (46.48%) as compared to male (38.46%).Escherichia coliwas the most common 346 (35.80 %) uropathogen followed byKlebsiella pneumoniae183 (18.92%) andEnterococcus species125 (12.92%). Gram negative isolates were most sensitive to imipenem (92%), ceftazidime-clavulanate (71%), piperacillin-tazobactam (68%), amikacin (60%), followed by nitrofurantoin (56%) as compared with fluoroquinolones. Gram positive isolates were most sensitive to vancomycin (91%) followed by linezolid (80%) and amoxycillin-clavulanic acid (45 %). Conclusion : UTI is a very common problem and rate of antibiotic resistance is relatively high. Imipenem, ceftazidime-clavulanic acid, piperacillin-tazobactam, amikacin, vancomycin and linezolid, were found sensitive against isolated uropathogens.

【 授权许可】

CC BY