Comparative Study of Ropivacaine 0.5% with fentanyl and Bupivacaine 0.5% with fentanyl in Interscalene Brachial Plexus Block

International Journal of Biomedical and Advance Research

Wasudeo Barsagade¹  A S Tarkase¹  Himmat Gate¹ 

关键词: Interscalene;    brachial plexus block;    Ropivacaine;    Bupivacaine;    fentanyl;   

DOI  :  10.7439/ijbar.v7i11.3747

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Aim and Objective:Aim of the present study was to compare the clinical characteristics of ropivacaine 0.5% and bupivacaine 0.5% with fentanyl when used for interscalene brachial plexus block. Methodology:In this prospective randomized double blind study, 60 patients were randomly divided into two groups, group BF-bopivacaine with fentanyl and group RF-ropivacaine with fentanyl. Effects in terms of onset, duration and quality of sensory and motor blockade, pulse and blood pressure, respiration were monitored and complications of interscalene brachial plexus block were also noted. Results:The mean onset time of sensory and motor blockade was 2.65 and 4.31 minutes in group BF and 4.08 and 6.08 minutes in group RF group respectively. The mean duration of sensory and motor block was 644.44 min and 595.55 min in group BF respectively. Whereas, in group RF the mean duration of sensory and motor block was 573.46 min and 513.46 min respectively. Mean VAS preoperatively was comparable among two groups perioperatively and till 7 hr after block placement (p> 0.05) all patient depicted a VAS score 0 up to 6 hr. The requirement of rescue analgesic was earlier with ropivacaine as compared to bupivacaine.Conclusion:Ropivacaine has the margin of safety than bupivacaine. Ropivacaine with an almost comparable blockade profile would be the better choice in view of safety of the patient.

【 授权许可】

CC BY