A study on analysis of Heart Rate Variability in hypertensive individuals

International Journal of Biomedical and Advance Research

Arun Kumar Balakrishnan¹  Nirmala Natarajan¹  Kavitha Ukkirapandian¹ 

关键词: Key words:Hypertension;    Autonomic nervous system;    Heart rate variability;   

DOI  :  10.7439/ijbar.v5i2.659

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Abstract: Introduction:Hypertension is a major risk factor for coronary artery disease, stroke and heart failure. Autonomic nervous system (ANS) dysfunction is an important factor in the development and progression of hypertension. Heart rate variability (HRV) is a simple, sensitive and non-invasive tool to monitor the cardiovascular ANS function. Thus, the present study was chosen as a simple tool to assess the sympathovagal balance by analysing the HRV changes in hypertensive individuals. Aims & Objectives:To analyse Heart Rate Variability (HRV) in hypertensive individuals. Materials & Methods:The study was conducted on 30 normotensive and 30 hypertensive subjects (BP?40/90 mm Hg, according to JNC-7 classification). Lead-II ECG was recorded using the instrument PHYSIOPAC-PP4, MEDICAID system, Chandigarh and HRV analysis was done using Kubios HRV analyser. Spectral indices of HRV such as total power (TP), normalized low frequency power (LFnu), normalized high frequency power (HFnu), ratio of low frequency power to high frequency power (LF-HF ratio), standard deviation of normal-to-normal RR intervals (SDNN), root mean square successive difference (rMSSD) and the proportion of NN50 to the total number of NN intervals (pNN50) were assessed.? Results:Our results showed significantly reduced HFnu (p<0.05), SDNN (p<0.05), rMSSD (p<0.05) and pNN50 (p<0.05) in hypertensive individuals. LFnu and LF-HF ratio was significantly increased (p<0.05) in hypertensive individuals. Conclusion:There is an increased sympathetic activity and a decreased vagal tone associated with hypertension. Thus, HRV can be used as a routine screening test to predict the future risk of hypertension at an earlier stage and also for a better prognosis during treatment.??

【 授权许可】

CC BY