Bacterial and parasitic etiological agents in HIV seropositive diarrhoea cases.

International Journal of Biomedical and Advance Research

Ranjana Namdeorao Thate¹  Vijayashree Deotale¹ 

关键词: Keywords: Kinyoun;    Trichrome;    HIV;    CD4 count;    diarrhea;    Parasitic;    bacterial.;   

DOI  :  10.7439/ijbar.v5i10.747

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Introduction:Studies in India indicated that diarrhoea has been the third common clinical presentation in AIDS patients. It is a second leading cause of hospital visit in developing nations and makes its place top ten worldwide. A diagnostic spectrum of enteric pathogen causing diarrhoea includes bacteria, parasites, fungi & viruses. Some pathogen tend to occur more frequently to cause more severe disease in person infected with HIV than in HIV uninfected persons with diarrhoea. These includeSalmonella spp., Isospora spp., Crytptosporidium spp., Microsporidia spp., Cytomegalovirus.Aims & Objectives:Present study was undertaken to find out which etiological agents are most commonly responsible for causing diarrhoea in HIV seropositive patients. Material Methods:Total 181 cases were included in study out which 150 were HIV seropositive and 31 were HIV seronegative. Diagnosis of HIV infection was done as per NACO guidelines and CD4 count estimation was done.? Isolation of bacterial pathogen was done using standard bacteriological procedures and parasite detection was done by direct examination after formal ether concentration technique, using staining as: modified Kinyoun?? acid fast staining and modified acid fast trichrome staining. Results:In this study, most common bacterial pathogen detected wasEscherichia coli ( 57.6%), followed byProteus spp(9.4%), %klebsiella spp ( 7.7%). Most common protozoal parasite wasCryptosporidium(53.6%), & Microsporidium (2.9%) ?and most common helminthic parasite wasS. stercoralis(1.6%).? All the enteric pathogens were predominantly detected with CD4+ count < 200 cells/ul. Conclusion: Cryptosporidiumwas the most common 53.6% parasitic enteropathogen detected while diarrheogenicE. coli18.2% was the most common bacterial enteropathogens isolated.? Majority of cases were with <200 ?CD4+ count had more than one pathogen.

【 授权许可】

CC BY