Microbial Profile ofNeonatal septicaemia in a tertiary care hospital of Bhopal

International Journal of Biomedical and Advance Research

Tukaram K Prabhu¹  Navinchandra M. Kaore¹  Abhishek Mehta¹ 

关键词: : Neonatal septicaemia;    Blood culture;    antibiotic susceptibility pattern;    Retrospective study.;   

DOI  :  10.7439/ijbar.v5i10.919

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Aims :To determine the microbial profile of neonatal septicaemia cases and ?antibiotic sensitivity pattern of aerobic isolates at a tertiary care hospital of ?Bhopal. Material and methods : In this retrospective study the laboratory data of blood ?culture reports of 256 neonates admitted to NICU,People?? Hospital,Bhopal ?with clinical suspicion of septicaemia from July 2012 to December 2013 was ?analyzed.? Results : Total 256 ?samples ?were ?received ?during ?the ?study ?period ?of ?which ?174 (68%) ?were ?found ?to ?be ?positive ?of ?which ?118(67.8%), 50(28.7%) ?and ?5(2.87%) ?had ?Gram ?positive,? Gram ?negative ?and ?Candidal ?infection ?respectively. Staphylococcus ?aureus ?and ?Klebsiella ?pneumoniae were ?the ?commonest ?isolates.Gram ?positive ?organisms ?were ?found ?to ?be ?most ?sensitive ?to ?Linezolid, Pristinomycin,? Cefoxitin ?and ?Vancomycin.Imipenem,? Levofloxacin ?and ?3 rdgeneration ?Cephalosporins ?were ?found ?to be ?most ?effective ?against ?Enterobacteriaceae ?group.Pseudomonas ?and ?Acinetobacter sp.? were ?found ?to ?be ?most ?susceptible ?to Imipenem,? Aztreonam ?and ?Piperacillin tazobactam. Conclusion : ?This ?study ?emphasizes ?the ?need ?for ?longitudinal ?surveillance ?to ?be ?carried ?at ?regular ?intervals ?to ?describe ?the ?varied ?pathogens ?causing neonatal sepsis as well as their changing antibiotic susceptibility pattern ?which ?will ?provide ?a ?useful ?information ?base ?to ?guide ?practise ?and ?policies ?on ?rational ?use ?of ?antibiotics.

【 授权许可】

CC BY