A Study on Role of Octreotide on Outcome of Patients with Acute Pancreatitis

International Journal of Biomedical and Advance Research

Lalitbhushan S Waghmare¹  Manish Swarnkar¹  Pankaj Gharde¹  Hrituraj Rohariya¹  Vijay Manohar Bhagat¹  Pramita Muntode¹  Vinay V Shahapurkar¹  Anoop Sharma¹  Dhirendra Dhairyashil Wagh¹ 

关键词: Acute Pancreatitis;    Octreotide;    Hospital Stay;    Mortality;   

DOI  :  10.7439/ijbar.v4i11.569

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Introduction:? Mild or edematous pancreatitis is a self limiting disease, morbidity and mortality is considerably high in cases of severe necrotizing pancreatitis. Octreotide is considered to be the drug which reduces the secretion of insulin, glucagon and vasoactive intestinal peptide. It also reduces splanchnic blood flow, gastrointestinal motility, absorption of water, electrolytes and nutrients from gut. Materials and method:? This retrospective study was done on patients admitted for the treatment of acute pancreatitis at a tertiary care hospital in Central India. The diagnosis of patients was established after biochemical and radiological investigations. The data of inpatient records were taken from the medical records department of the hospital. Results:? The mean age in octreotide group (Group A) was 35 ??16.45 years and 40???17.51 years in Group B (t? A/B ?1.061; p??0.294). Both the groups were comparable gender wise; there was no significance (X 2 ?=0.12, p

【 授权许可】

CC BY