A STUDY OF FVC, PEFR AND MEP IN DIFFERENT TRIMESTERS OF PREGNANCY

International Journal of Biomedical and Advance Research

Shrilaxmi Bagali¹  Manjunatha Aithala¹  Anita Teli¹ 

关键词: Pregnancy;    FVC;    PEFR;    MEP;   

DOI  :  10.7439/ijbar.v3i8.609

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Objective: Pregnancy is characterized by profound changes in the function of virtually every regulatory system in the human body. The events in pregnancy elicit one of the best examples of selective anatomical, physiological & biochemical adaptation that occur during pregnancy & profound changes in respiratory physiology is a part of the same process. Thus this study was designed to evaluate the pulmonary function tests in 1 st , 2 ndand 3 rdtrimesters of pregnancy & compare them with non-pregnant control group.Method :A cross-sectional study was carried in 200 healthy women in the age range of 19-35 years .The subjects were distributed in four groups, i.e control (non-pregnant) group and 1 st, 2 nd&3 rdtrimester pregnant groups. Number of subjects in each group is 50. We recorded respiratory parameters in control and study groups. Statistical analysis done by ???????? test.Result:There was significant decrease in FVC, PEFR & MEP in all trimesters of pregnancy with maximum decrease of FVC in 1 sttrimester &?? PEFR, MEP in 2 ndtrimester.Conclusion:The changes in pulmonary function?? are attributed to major adaptations in the maternal respiratory system & are also be influenced by?? the mechanical pressure of enlarging gravid uterus, elevating the diaphragm & restricting the movements of lungs thus hampering the forceful expiration & decrease in 1 sttrimester?? might be due to decline in alveolar Pco 2caused by hyperventilation which acts as bronchoconstrictor & due to sensitization of respiratory centre due to progesterone. "

【 授权许可】

CC BY