Steroid injection in chronic inflammatory vocal fold disorders, literature review

Revista Brasileira de Otorrinolaringologia

Sennes, Luís Ubirajara¹  USP¹  Tsuji, Domingos Hiroshi¹  Universidade de São Paulo¹  Campagnolo, Andrea Maria¹  Imamura, Rui¹ 

关键词: vocal fold scarring;    steroids;    steroid injection;    inflammatory lesions of vocal fold;    laryngeal disease.;   

DOI  :  10.1590/S0034-72992008000600017

学科分类：医学（综合）

来源: Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial

【 摘 要 】

Steroids are potent inhibitors of inflammation and wound repair. Local administration of steroids directly into the larynx has been reported in many laryngeal diseases. AIM: The purpose of this study is to review related literature about the use of steroid injection in patients with benign, inflammatory and chronic vocal disease. METHODOLOGY: We performed an electronic survey in Medline database and selected clinical trials regarding steroid use in benign laryngeal diseases. RESULTS: Steroids are indicated in these situations: 1) acute inflammatory diseases, mainly when edema compromises the airways; 2) auto- immune disease with laryngeal involvement; 3) laryngeal stenosis; 4) benign lesions of the vocal folds, e.g., nodules, polyps and Reinke's edema, to reduce the inflammatory reactions before phonosurgery or in an attempt to avoid surgery; 5) In phonosurgery, aiming to reduce scarring. In this case, it could be used as a preventive measure in vocal fold scarring, or for scar treatment. CONCLUSION: Steroids may be considered an important therapeutic option in the management of many diseases, specially the inflammatory ones, associated with vocal changes.

【 授权许可】

Unknown