Correlation between TNM classification and malignancy histological feature of oral squamous cell carcinoma

Revista Brasileira de Otorrinolaringologia

Araújo Júnior, Raimundo F. de¹  Faculdade Santa Maria¹  Hospital Dr. Luiz Antônio, Natal¹  Ramos, Carlos C. F.¹  UFRN¹  Costa, Antonio de L. L.¹ 

关键词: prognosis;    oral squamous cell carcinoma;    histologic grading;    oral pathology.;   

DOI  :  10.1590/S0034-72992005000200011

学科分类：医学（综合）

来源: Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial

【 摘 要 】

Histological staging of deep invasive margin of oral squamous cell carcinoma has a significant influence on survival of patients since the tumor cells are more poorly differentiated in this area and have high prognostic value.AIM: the purpose of the present study is to correlate TNM clinical classification with histopathologic characteristics (degree of keratinization, nuclear pleomorphism, invasion pattern and lymphoplasmocytic infiltrate) and histologic malignancy scores in 38 cases of oral epidermoid carcinoma in the lesion's deepest areas.STUDY FORM: Retrospective clinical study.MATERIAL AND METHOD: This is a retrospective study based on histological review of 38 cases of oral squamous cell carcinoma selected from the medical files of Hospital Dr. Luis Antonio, Natal - Rio Grande do Norte, Brazil. TNM clinical classification data were obtained from the analysis of the medical records. Two pathologists performed histological malignancy staging on routine 3 µm-thick sections of invasive tumor areas stained with hematoxylin and eosin. For statistical analysis, parametric (ANOVA) and non-parametric tests (Tu

【 授权许可】

Unknown