Otoacoustic emissions x Cisplatin: precocious detection of ototoxicity in oncologic patients

Revista Brasileira de Otorrinolaringologia

Clínica de Otorrinolaringologia de Blumenau¹  Zocoli, Ruysdael¹  Policlínica Lindolf Bell¹  Zocoli, Ângela Maria Fontana¹  Hospital Santa Catarina¹  Reichow, Sandro Laércio¹ 

关键词: hearing;    otoacoustic emissions;    ototoxicity;    cisplatin.;   

DOI  :  10.1590/S0034-72992003000200012

学科分类：医学（综合）

来源: Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial

【 摘 要 】

Studies show that there are numerous substances known as potentially ototoxic and among the main ones in the medicine classes, stands out the chemotherapeutics.AIM: The objective of this work was to achieve a study of the ototoxicity through otoacoustic emissions – product of distortion (EOA – PD), pre and post-application of the chemotherapeutic Cisplatin, in adults individuals, residents of the city of Blumenau/SC.STUDY FORM: Clinic prospective.MATERIAL AND METHOD: There were 11 individuals studied with oncologic pathology, age between 29 and 73 years old, through the otoacoustic emissions– product of distortion, previous and subsequently to the Cisplatin application, using the Madsen Cappela equipment coupled to the notebook Toshiba satellite computer.RESULTS: The results didn't show significant changes on the answers of the EOA – PD on the frequencies of 2, 3 and 4 kHz, however, in 1 and 6 kHz, alterations occurred on the hearing sensitivity after the Cisplatin application.

【 授权许可】

Unknown