Histopathological analysis of oral cancer cases in health institutions of Maule and Bío-Bío Chilean regions between the years 2001-2011

Revista clínica de periodoncia, implantología y rehabilitación oral

Universidad Estatal de Campinas, Piracicaba, Brasil¹  Donoso, Wendy¹  Contreras-Ramírez, Manuel¹  Rivera, César¹  Universidad de Talca, Talca, Chile¹  Centro Nacional de Investigación en Energía y Materiales, Campinas, Brasil¹  Hospital Carlos Van Büren, Valparaíso, Chile¹  Venegas, Bernardo¹ 

关键词: Oral squamous cell carcinoma;    Oral cancer;    Mouth neoplasms;    Chilean population;   

DOI  :  10.1016/j.piro.2015.06.005

来源: Sociedad de Periodoncia de Chile

【 摘 要 】

Squamous cell carcinoma of the oral cavity (OSCC) is an invasive epithelial neoplasm with varying degrees of differentiation and propensity to metastasise. Chilean evidence for OSCC is scarce, and even more so for the Seventh (Maule) and Eighth (Bío-Bío) regions. Hence, the present study is carried out to evaluate the histopathological features of OSCC patients to contribute to local and national knowledge. A retrospective observational study was conducted on a convenience sample (n = 33) from health care institutions of Seventh and Eighth Chilean regions. The mean age of patients was 65 years. The most common OSCC anatomical locations were lips (36.4%), followed by the tongue (27.3%), and the floor of the mouth (9.1%). Moderately differentiated OSCC predominated (51.5%), with a pattern of infiltrating tumour invasion (81.8%) and a moderate/strong immune response (75.8%). In these Chilean regions, OSCC mainly affects older people and is located in an easily accessible area for anatomical examination, which should allow early diagnosis. Professionals with post-graduate knowledge or expertise in Pathology and Oral Medicine are needed in public health care centres.

【 授权许可】

Unknown