Current Oncology | |
Extracellular–to–body cell mass ratio and subjective global assessment in head-and-neck cancers | |
A. Smolen1  K. Morshed1  T. Małecka-Massalska1  | |
[1] Medical University of Lublin | |
关键词: Head-and-neck cancer; bioelectrical impedance analysis; extracellular–to–body cell mass ratio; subjective global assessment; | |
DOI : | |
学科分类:肿瘤学 | |
来源: Multimed, Inc. | |
【 摘 要 】
BackgroundThe ratio of extracellular mass to body cell mass (ecm/bcm), determined by bioelectrical impedance analysis, has been found to be a potentially useful indicator of nutrition status. Subjective global assessment (sga) is a subjective method of evaluating nutrition status in head-and-neck cancer. The present study was conducted to investigate the association between ecm/bcm and sga in head-and-neck cancer. Methods Patients were classified as either well-nourished or malnourished by sga. Bioelectrical impedance analysis was conducted on a population of 75 patients with histologically confirmed head-and-neck cancer, and the ecm/ bcm was calculated. Receiver operating characteristic curves were estimated using the nonparametric method to determine an optimal cut-off value of the ecm/bcm. Results Compared with malnourished patients, those who were well-nourished had a statistically significantly lower ecm/bcm (1.11 vs. 1.28,p= 0.005). An ecm/bcm cut-off of 1.194 was 76% sensitive and 63% specific in detecting malnutrition. Conclusions The ecm/bcm can be an indicator that detects malnutrition in patients with head-and-neck cancer. Further observations are needed to validate the significance of the ecm/bcm and to monitor nutrition interventions.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912050597926ZK.pdf | 553KB | download |