Determination of flavonoids in stamen, gynoecium, and petals of Magnolia grandiflora L. and their associated antioxidant and hepatoprotection activities

Química Nova

Sokkar, Nadia M.¹  National Organization for Drug Control and Research, Egypt¹  King Abdulaziz University, Jeddah, Saudi Arabia¹  Rabeh, Mohamed A.¹  National Research institute Dokki, Giza, Egypt¹  Slem, Amani M.¹  Cairo University, Cairo, Egypt¹  Ghazal, Gamal¹ 

关键词: Magnolia grandiflora L.;    antioxidant flavonoids;    hepatoprotection.;   

DOI  :  10.5935/0100-4042.20140106

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Chromatographic analysis of flavonoids in ethyl acetate fractions of the stamen, gynoecium, and petal of Magnolia grandiflora L. by HPLC-PDA-MS/MS-ESI in the negative ionization mode was performed in this study. The results revealed the presence of eight flavonoids: apigenin 8-C-glucoside, luteolin 8-C-glucoside, quercetin 3-O-rutinoside, quercetin 3-O-galactoside, quercetin, 3-O-glucoside, kaempferol 3-O-rutinoside, isorhamnetin 3-O-glucoside, and isorhamnetin. Their quantification revealed that luteolin 8-C-glucoside is the major flavonoid and that the total phenolic content is concentrated primarily in the stamen. The antioxidant and hepatoprotective effects of ethanolic extract of the flower organs were evaluated against hepatotoxicity induced by CCl4, compared with the effects of silymarin.

【 授权许可】

Unknown