Metabolomics, an optimized approach for the rational exploitation of Brazilian biodiversity: state of the art, new scenarios, and challenges

Química Nova

Bolzani, Vanderlan da Silva¹  Universidade Estadual Paulista, Araraquara, Brasil¹  Castro-Gamboa, Ian¹  Funari, Cristiano Soleo¹  Cavalheiro, Alberto José¹ 

关键词: biodiscovery;    metabolite profile;    analytical techniques.;   

DOI  :  10.1590/S0100-40422013001000019

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Brazilian biodiversity is a colossal source of secondary metabolites with remarkable structural features, which are valuable in further biodiscovery studies. In order to fully understand the relations and interactions of a living system with its surroundings, efforts in natural product chemistry are directed toward the challenge of detecting and identifying all the molecular components present in complex samples. It is plausible that this endeavor was born out of recent technological sophistication in secondary metabolite identification with sensitive spectroscopic instruments (MS and NMR) and higher resolving power of chromatographic systems, which allow a decrease in the amount of required sample and time to acquire data. Nevertheless, the escalation of data acquired in these analyses must be sorted with statistical and multi-way tools in order to select

【 授权许可】

Unknown