Clerodane diterpenes from leaves of Casearia sylvestris Swartz

Química Nova

Perez, Carla C.¹  Santos, André G. dos¹  Universidade Estadual Paulista 'Júlio de Mesquita Filho', Araraquara, Brasil¹  Cavalheiro, Alberto J.¹  Tininis, Aristeu G.¹  Bolzani, Vanderlan da S.¹ 

关键词: Casearia sylvestris;    clerodane diterpenes;    15-hydroxy-3-cleroden-2-one.;   

DOI  :  10.1590/S0100-40422007000500009

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Ethanolic extracts of the leaves of Casearia sylvestris yielded a novel clerodane diterpene, 15-hydroxy-3-cleroden-2-one, together with the known diterpenes (-)-hardwickiic acid, reported for the first time from this species, and casearins B and G, previously isolated from C. sylvestris. The structures of all four compounds were determined by spectrometric analysis. The new clerodane diterpene and (-)-hardwickiic acid contain structural features that are completely different from the highly oxygenated casearins and casearvestrins isolated from C. sylvestris.

【 授权许可】

Unknown