HIV-integrase inhibitors: potential pharmacological approach for AIDS therapy

Química Nova

Melo, Eduardo Borges de¹  Bruni, Aline Thaís¹  Ferreira, Márcia Miguel Castro¹ 

关键词: AIDS;    HIV;    integrase.;   

DOI  :  10.1590/S0100-40422006000300026

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

AIDS has the HIV as its etiological agent. Researches has been done to find new pharmacological agents to be used in therapy, because of problems of resistance and side effects. The HIV-integrase inhibitors are some of those new agents that are being studied. This updating focusses on the fundamental information about HIV and HIV-integrase and the main methods being used to develop these new drugs, with examples for each case.

【 授权许可】

Unknown