Validation of the analytical methodology for evaluation of lapachol in solution by HPCL

Química Nova

Universidade Federal de Pernambuco, Recife¹  Fonseca, Said G. C.¹  Silva, Leila B. L. da¹  Santana, Davi P. de¹  Castro, Rebeka F.¹  Universidade Federal do Ceará, Fortaleza¹ 

关键词: lapachol;    validation;    HPLC.;   

DOI  :  10.1590/S0100-40422004000100026

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Lapachol is a naphthoquinone found in several species of the Bignoniaceae family possessing mainly anticancer activity. The present work consists of the development and validation of analytical methodology for lapachol and its preparations. The results here obtained show that lapachol has a low quantification limit, that the analytical methodology is accurate, reproducible, robust and linear over the concentration range 0.5-100 µg/mL of lapachol.

【 授权许可】

Unknown