Chemical Profiling of Ginseng Species and Ginseng Herbal Products Using UPLC/QTOF-MS

Journal of the Brazilian Chemical Society

Olivos, Hernando J.¹  Patel, Dhavalkumar N.¹  Isaac, Giorgis¹  Waters Pacific Pte Ltd, Singapore¹  Waters Corporation, Milford, USA¹  Yuk, Jimmy¹  Smith, Kerri¹  Yu, Kate¹  Wrona, Mark¹ 

关键词:  metabolic profiling;    natural product;    mass spectrometry;    authentication;    LC-MS;   

DOI  :  10.5935/0103-5053.20160189

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The chemical profiles of four ginseng roots samples from three species of ginseng (Panax quinquefolius, Panax ginseng and Panax notoginseng) and two commercial ginseng products containing P. quinquefolius and red P. ginseng were compared using ultra-performance liquid chromatography coupled with quadrupole time of flight mass spectrometry (UPLC/QTOF-MS). Principal component analysis allowed a holistic approach in showing distinct chemical differences between the three ginseng species and correct classification of the two commercial products to their respective species. Further investigation of the chemical profile variations yielded ten main markers that were distinct for the three species. This study shows the potential of chemical profiling for the classification of complex natural product samples, such as ginseng, and application to commercial products sold in the market. This methodology can assist the industry in authenticating the various species of ginseng and providing a quick assessment of the quality of commercial ginseng products.

【 授权许可】

Unknown