Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum

Journal of the Brazilian Chemical Society

Marinho, Andrey M. R.¹  Marinho, Patrícia S. B.¹  Pinheiro, Eduardo A. A.¹  Barison, Andersson¹  Feitosa, André O.¹  Souza, Afonso D. L.¹  Universidade Federal do Amazonas, Manaus, Brazil¹  Ferreira, Leila R. S.¹  Carvalho, Josiwander M.¹  Cordeiro, Jorgeffson S.¹  Universidade Federal do Pará, Belém, Brazil¹  Campos, Francinete R.¹  Universidade Federal do Paraná, Curitiba, Brazil¹  Pina, Jeferson R. S.¹  Borges, Fabio C.¹ 

关键词:  annularins;    polyketides;    E. rostratum;    endophytic fungi;   

DOI  :  10.5935/0103-5053.20160140

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The paper describes the isolation of ergosterol peroxide, monocerin, annularin I and annularin J compounds of Exserohilum rostratum biomass extracts. Compounds were isolated by silica gel column chromatography in polarity gradient and the structures were determined by nuclear magnetic resonance (NMR) and mass spectrometry (MS) methods. Monocerin, annularin I and annularin J compounds were tested against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis bacteria and showed moderate activity. Annularin I and annularin J compounds are new natural products.

【 授权许可】

Unknown