Fast Microwave-Assisted Resolution of (±)-Cyanohydrins Promoted by Lipase from Candida antarctica

Journal of the Brazilian Chemical Society

Universidade de São Paulo, São Carlos, BR¹  Ribeiro, Sandra S.¹  Ferreira, Irlon M.¹  Santos, Alcindo A. Dos¹  Sousa, Bruno A. de¹  Porto, André L. M.¹  Carmona, Rafaela C.¹  Lima, João P. F.¹  Universidade de São Paulo, São Paulo, BR¹ 

关键词:  CALB;    biocatalysis;    enzymatic resolution;    microwave radiation;    cyanohydrins;   

DOI  :  10.5935/0103-5053.20150102

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Enzymatic kinetic resolution (EKR) of (±)-cyanohydrins was performed by using immobilized lipase from Candida antarctica (CALB) under conventional ordinary conditions (orbital shaking) and under microwave radiation (MW). The use of microwave radiation contributed very expressively on the reduction of the reaction time from 24 to 2 h. Most importantly, high selectivity (up to 92% eep) as well as conversion was achieved under MW radiation (50-56%).

【 授权许可】

Unknown