Simultaneous determination of different classes of pesticides in breast milk by solid-phase dispersion and GC/ECD

Journal of the Brazilian Chemical Society

Mello, Paulo R. B.¹  Pignati, Wanderlei A.¹  Uecker, Marli E.¹  Palma, Danielly C. A.¹  Universidade Federal de Mato Grosso, Cuiabá, Brazil¹  Universidade Federal de Mato Grosso¹  Dores, Eliana F. G. C.¹  Lourencetti, Carolina¹ 

关键词: pesticides;    solid-phase dispersion;    gas chromatography;    breast milk;    matrix effect;   

DOI  :  10.5935/0103-5053.20140124

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

This study presents the development, validation and application of a multiresidue analytical method intended to determine nine pesticides and a degradation product (α-endosulfan, β-endosulfan, α-HCH, g-HCH, aldrin, p,p'-DDE, p,p'-DDT, cypermethrin, deltamethrin, and trifluralin) in breast milk samples by solid-phase dispersion and gas chromatography with electron capture detector (GC/ECD). The proposed method is considered simple and efficient, combining extraction and clean up in a single step and quantification performed by standard addition to avoid the matrix effect. The method limits of detection and quantification varied between 0.002 and 0.079 µg mL–1 and 0.013 and 0.108 µg mL–1, respectively. The proposed method was applied to analyze 62 breast milk samples collected between February and June 2010 in Lucas do Rio Verde, Mato Grosso, Brazil. p,p'-DDE (0.32-12.03 µg g–1 of fat), p,p'-DDT (2.62-12.41 µg g–1 of fat) and β-endosulfan (0.54-0.61 µg g–1 of fat) were quantified in 29%, 5% and 3% of the samples, respectively. Aldrin was found below the method quantification limit in 7% of samples. Although these compounds were found in the analyzed samples, mothers were oriented to carry on feeding the infants as the breast milk is considered the optimum food during infancy.

【 授权许可】

Unknown