UV filters in water samples: experimental design on the SPE optimization followed by GC-MS/MS analysis

Journal of the Brazilian Chemical Society

São Paulo State University, Araraquara, Brazil¹  Marchi, Mary R. R. de¹  Emídio, Elissandro S.¹  Silva, Claudia P. da¹ 

关键词: UV filters;    solid-phase extraction;    experimental design;    GC-MS/M;   

DOI  :  10.5935/0103-5053.20130182

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

This study describes the development and optimization of a solid-phase extraction (SPE) method for analysis of ultraviolet (UV) filters, benzophenone-3 (BP-3), ethylhexyl methoxycinnamate (EHMC), ethylhexyl salicylate (ES) and octocrylene (OC), in environmental matrices. A 25-1 fractional factorial design (FFD) was used to evaluate the significant variables for the extraction method. The optimized experimental conditions determined from the statistical evaluation were: breakthrough volume of 500 mL, eluent of ethyl acetate, wash solvent of methanol (10% in water, v/v), eluent volume of 3 × 2 mL and pH 3. The evaluated analytical parameters were satisfactory for the analytes and showed linearity between 100 and 4000 ng L-1, recoveries for four fortification levels (Method Quantification Limit, 200, 1000 and 2000 ng L-1) were between 62 and 107% with relative standard deviations less than 14%. Limits of quantification were in the ng L-1 range and were between 10 and 100 ng L-1. The proposed method was used to analyze four UV filters in natural water samples.

【 授权许可】

Unknown